I do some outbound, and it seems I have more luck with .org. I was able to sell 2 .org to customers who own the .com. On the other hand, I was unable to sell a .co to some guys who own .net. Of course, this is not a rule, just my experience.
It depends entirely on the business, and the market that you operate within. Additionally, consider both the way the extension sounds in conjunction with the business name, AND who your target demographics are.
I am not a big fan of .co, but for a business I would probably prefer it more than an .org. Personally I do not like brand names ending with .org that much.
It also depends. I had great success (steady income) with a destination website with an .org.
I would not use .org for a business.
So if .com definitely not available I would consider .co along with .net and .io and possibly others.
I would also consider a new gTLD if one fits the business well, or possibly one of the generic ones like .site or .xyz.
Depends on what kind of website you're planning on:
- for most types of corporate sites - .CO
- for a portal, info website, branding, business support services company - .ORG hands down! Inspires much more confidence than an obscure (as in: unknown to most people) Colombia ccTLD